Rejuran often comes up when people are looking into concerns around the eye area, fine lines or changes in skin texture. Those are quite broad descriptions, though, and they don’t always tell you whether the treatment is relevant to what you’re actually seeing.
Fine lines, crepey-looking skin, dark circles and hollows can all show up around the eyes, but for different reasons. That matters, because Rejuran may be more relevant to some of those changes than others.
This guide looks at what Rejuran is generally used for, the types of concerns it may suit, where its limitations are, and what treatment involves. It should also give you a clearer idea of whether the result Rejuran is intended to produce lines up with what you want to improve.
First, what kind of treatment is Rejuran?
Rejuran is an injectable gel containing sodium polynucleotide – purified DNA fragments derived from salmon.
Rejuran is placed into the dermis through a series of small injection points, with the treatment directed at the skin itself.
This is why Rejuran is usually discussed in relation to skin quality, particularly texture and fine lines.
Who might Rejuran suit?
Rejuran may suit you if your main concerns are fine lines, changes in texture or thin or crepey-looking skin, and you’re comfortable with a gradual, relatively subtle change.
Rejuran may be less suitable if you want a dramatic or immediate change, are mainly concerned with hollowing or another structural issue, or are hoping it will improve deeper wrinkles or every type of under-eye darkness.
Treatment may not be appropriate during pregnancy or breastfeeding, if there is an active infection or inflammation in the area being treated, or if you have a known hypersensitivity to Rejuran or any of its ingredients.
Other health conditions, medications and recent treatments may also affect suitability.
Rejuran contains polynucleotides derived from salmon. If you have a known fish or salmon allergy, make sure you mention this as part of your medical history.
Where can Rejuran be used?
Rejuran can be used in several areas of the face. Whether it makes sense depends on the type of skin change you’re looking to address.
Around the eyes, Rejuran is generally considered for fine lines, thin or crepey-looking skin and changes in texture.
Dark circles and hollowing need a closer look because pigmentation, visible blood vessels, thin skin and structural shadowing can all create a similar appearance. Rejuran may not be relevant to every under-eye concern.
Across the cheeks and mid-face, Rejuran is generally considered for concerns such as fine lines, uneven texture, visible pores and dry-looking skin.
Rejuran may also be considered for fine lines and changes in skin quality around the mouth.
Lines in this area can have different contributing factors, so whether Rejuran is relevant depends on what is contributing to their appearance.
What are the possible side effects and risks of Rejuran?
Temporary reactions can occur around the treatment points after Rejuran.
These may include redness, swelling, tenderness or discomfort, bruising and small raised bumps. How noticeable these reactions are and how long they last can vary from person to person and depending on the area treated.
There is also a risk of infection whenever the skin is broken during treatment.
What does a realistic Rejuran result look like?
“Subtle” comes up a lot when people talk about Rejuran, but it can mean different things to different people.
Rejuran is more likely to appeal if the changes you want are mostly about fine lines, texture and the overall quality of the skin. For some people, even a modest improvement in these areas feels like enough.
It may be disappointing if you’re expecting a dramatic before-and-after, a noticeable change to deeper wrinkles, or correction of hollowing or other structural changes. The same applies if under-eye darkness is your main concern, as not every type of darkness is related to the skin itself.
At Laser Skin & Vein, we favour natural-looking results. With Rejuran, that usually means an improvement you can notice without the treatment itself looking obvious.
Everyone has a different idea of what feels like enough. A subtle improvement may be exactly what you’re looking for, or it may simply not be enough.
How many treatments are usually involved?
Rejuran is usually planned as a course of treatments, with around three sessions being a common starting point. These are often spaced 2–4 weeks apart, although the exact plan can vary depending on the area being treated, the concern and how your skin responds.
Your initial treatment plan. During your consultation at Laser Skin & Vein, one of our registered nurses will assess the area you’d like treated and talk you through the proposed plan, including how many sessions we recommend and why.
Timing between appointments. Your plan will also include the suggested intervals between treatments, so you can factor them into work, travel and other commitments.
When your progress will be reviewed. We’ll assess how your skin is responding before discussing whether any further treatment makes sense.
Maintenance later on. This can be discussed once you’ve seen how your skin responds and whether the change feels worthwhile to you.
What happens if the result isn’t what you expected. You can then discuss whether it makes sense to continue, adjust the approach or leave it there.
What does recovery actually look like?
Rejuran can remain visible for a while after treatment. Small raised bumps may appear at the treatment points, along with redness, swelling, tenderness or bruising.
Some people notice very little, while for others the signs of treatment are more noticeable for a few days. This can also vary depending on where Rejuran has been used.
Straight after treatment. Small raised bumps can be visible where Rejuran has been placed. Redness, swelling or tenderness can also occur.
Over the next few days. The bumps and swelling may start to settle, although they can remain visible for longer, particularly around the eyes. Bruising may take longer to fade.
As the area settles. We’ll talk you through the recovery window you may need to allow for the area being treated, so you can plan around work, travel or any upcoming events.
Work. If visible bumps, redness or swelling would bother you at work, you may want to allow some extra time for the area to settle.
Events or photographs. If you have something important coming up, let us know before choosing a treatment date. We can take the expected recovery window into account when planning your appointment.
Rejuran or something else?
The same visible change can happen for different reasons, and that can affect which treatment is likely to be relevant.
Rejuran is generally considered in relation to skin quality, including fine lines, changes in texture and thin or crepey-looking skin. If facial movement, structure, pigmentation or visible vessels are playing a bigger role, another approach may make more sense.
This is particularly relevant around the eyes, where several different things can create a similar appearance.
If you’re noticing… | We would look at… |
Fine lines, texture changes or thin-looking skin | Whether Rejuran is appropriate for the area and the type of skin change |
Lines that appear mainly with facial movement | How much movement is contributing to the lines |
Hollowing or shadowing | Whether facial structure is creating the appearance |
Pigmentation or visible vessels | Whether a laser or energy-based treatment may be relevant |
General skin maintenance | Your current skincare, sun protection and whether an in-clinic treatment would add anything useful |
At Laser Skin & Vein, the consultation starts with what you want assessed. We’ll look at what appears to be contributing to the change and explain whether Rejuran is relevant in your case.
Rejuran and laser or energy-based treatments
Rejuran and laser or energy-based treatments are used for different types of concerns.
Rejuran is generally discussed in relation to skin quality. Depending on the device and its intended use, laser or energy-based treatments may be more relevant for concerns such as pigmentation, visible vessels or resurfacing.
Sometimes more than one type of treatment may be appropriate. If that’s the case, we can explain what each one is intended to address and how they might fit together.
Rejuran and PRP
PRP is another treatment people often compare with Rejuran when looking at options for skin quality.
Rejuran is a manufactured medical device with a specified composition, while PRP is prepared from the patient’s own blood.
There isn’t strong head-to-head evidence to show that Rejuran is better than PRP across the board, so we wouldn’t present it that way. What may suit you depends on the area being treated and the type of change you want to address.
Is Rejuran worth considering – and where should you start?
If you’re interested in Rejuran but aren’t sure whether it suits what you want to address, a consultation is the place to start.
At Laser Skin & Vein in North Adelaide or Malvern, we’ll assess the area you’re concerned about, look at what may be contributing to the change and explain whether Rejuran is appropriate – including what kind of result would be realistic to expect.
If treatment is recommended, we’ll talk you through:
- why we’re recommending it
- the likely number of treatments
- what recovery may look like
- the expected cost of the course
- when we would review your progress
If another approach is likely to be more suitable, we’ll explain that as well.
You’ll leave with a clearer idea of what we recommend and what the proposed course would involve, so you can decide whether you want to proceed.
Book a consultation to find out whether Rejuran may be appropriate for you.
